She first appeared on television in a street theatre play, televised for 8 March, for the program Aadhi Duniya in 1989. The play was Aurat. She was the first announcer for Network Television Marketing, Karachi center. She then appeared in Haseena Moin's serial Aahat, directed by Sahira Kazmi, followed by Anwar Maqsood's Sitara Aur Mehrunissa directed by Zark in 1991 & 1992 respectively, which shot Sania to her stardom in the Pakistani television Industry. Sania has been working in theatre and television for over two decades.
She won PTV Award for Best Actress in 1991 as well as in 2011 and received four Lux Style Awards in the Best Actress category. She has appeared opposite Zuhab Khan, Shamoon Abbasi, Ismat Zaidi, Soniya Hussain, Badar Khalil, Khalid Ahmed and Sana Askari in many episodes of Kitni Girhain Baqi Hain