Ameer Buksh Khan Bhutto (Urdu: امیر بخش خان بھٹو ) is Vice President of the Sindh National Front and an ex-Member of the Sindh Assembly. He is the son of Sardar Mumtaz Bhutto. 
He holds a B.A. in Politics, Economics & Law from the University of Buckingham and a M. Phil in International Relations from Cambridge University. He wrote a thesis titled "Of Knights and Harlots: The Role of the Superpowers in the 1971 Indo-Pakistan War." He has also written dozens of articles published in English and Sindhi newspapers and magazines in Pakistan.
He ran for the seat of the Provincial Assembly of Sindh twice, in 2002 general election and again in 2008 election but defeated twice by Muhammad Ayaz Soomro.
On 10 November 2017, Ameer Buksh Khan Bhutto while meeting with Shah Mehmood Qureishi, announced to join Pakistan Tehreek-e-Insaf.